A STOCHASTIC COVARIANCE SHRINKAGE APPROACH IN ENSEMBLE TRANSFORM KALMAN FILTERING





Heterogeneous Cytoskeletal Force Distribution Delineates the Onset Ca2+ Influx Under Fluid Shear Stress in Astrocytes

Mechanical perturbations increase intracellular Ca2+ in cells, but the coupling of mechanical forces to the Ca2+ influx is not well understood.We used a microfluidic chamber driven with a high-speed pressure servo SMA to generate defined fluid shear stress to cultured astrocytes, and simultaneously measured cytoskeletal forces using a force sensiti

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